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3-FPM | 3-Fluorophenmetrazine

3-FPM, or 3-Fluorophenmetrazine is a novel chemical of the Phenylmorpholine class.

“3-FPM acts as a norepinephrine-dopamine releasing agent with EC50 values of 43 nM and 30 nM, respectively.[3][4] It shows only negligible efficacy as a releaser of serotonin, with an EC50 value of 2558 nM.[3]

3-FPM also inhibits uptake mediated by dopamine transporters and norepinephrine transporters in HEK293 cells […] (IC50 values < 2.5 μM), but with less potent effects at serotonin transporters (IC50 values >80 μM).[4]

At sufficient doses, 3-FPM is capable of reversing monoamine transporters, particularly transporters of the catecholamines dopamine and norepinephrine, and, to a much lesser degree, serotonin transporters, thereby releasing these neurotransmitters from the cytosol into the extracellular space, where they are active.[4]

Evaluation of its metabolic pathway revealed N‐oxidation, aryl hydroxylation and subsequent O‐methylation, alkyl hydroxylation, oxidation, and degradation of the ethyl‐bridge yielding the O/N‐bis‐dealkylated metabolite, combinations thereof and further glucuronidation or sulfations.[5]
-Excerpt from WikiPedia

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Like all other of our other Research Chemicals we offer, our 3-FPM is guaranteed to be genuine and of utmost purity. Most importantly, all of our products are traced & identified by lot number. You can shop with Canada Chems confidently knowing we have your research team’s safety in mind.

You may click on this link to find our most up to date MSDS (Material Safety Data Sheet) for this product.

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About this molecule
CAS Registry Number:  
PUBCHEM Registry Number :  
1350768-28-3 HCl1803562-83-5 7
5481405 HCl54673723  
34212559 HCl3750994
Molecular Formula:C11H14FNO
Molecular Weight:195.2333 g/mol
Purity:< 99.0%